Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and. Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. Eur J Haematol Suppl. Mar;(71) doi: /j x. Immune thrombocytopenic purpura: epidemiology and implications for.
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Treatment should be restricted to those patients with moderate or severe thrombocytopenia who are bleeding or at risk of bleeding.
The IgG autoantibodies are also thought to damage megakaryocytesthe precursor cells to platelets, although this is believed to contribute only slightly to the decrease in platelet numbers. The major causes of accelerated platelet consumption include immune thrombocytopenia, decreased bone marrow production, and increased splenic sequestration.
This increased risk of death with ITP is largely concentrated in the middle-aged and elderly. The patient continued to take Pantaprazole orally 40mg twice daily for 6 weeks and was advised to use wysolone S.
An ITP patient with an extremely low count is vulnerable to internal bleeding caused by blunt abdominal traumaas might be experienced in a motor vehicle crash. National Center for Biotechnology InformationU. ITP may be either acute or chronic. Autoimmune thrombocytopenic Purpura and Helicobacter pylori infection. There is no accepted platelet count that defines an indication for initial treatment. First, one has to make sure that there are no other blood abnormalities except for low platelet count and no physical signs except for signs of bleeding.
Idiopathic thrombocytopenic purpura
Bone marrow examination may be performed on patients over the age of 60 and those who do not respond to treatment, or when the diagnosis is in doubt. Accepted Feb 5. Systemic lupus erythematosus Subacute bacterial endocarditis Rheumatoid arthritis. Corticosteroids, typically prednisone, are the backbone of the initial treatment.
Immune thrombocytopenic purpura
In the United States, the adult chronic population is thought to be approximately 60,—with women outnumbering men approximately 2 to 1, which has resulted in ITP being designated an orphan disease. Allergic contact dermatitis Mantoux test. Diseases of trrombositopeni skin and appendages by morphology. She suffered from bleeding gums with the appearance of generalized purple spots all over the body, bleeding into the right eye and melena since last 10 days.
Immune thrombocytopenic purpura – Wikipedia
Most cases respond during the trojbositopeni st week of treatment. It is recommended that pregnant women with thrombocytopenia or a previous diagnosis of ITP should be tested for idiopatiik antiplatelet antibodies. The evolution of drug discovery: Petechia of the lower leg in a person with platelets of 3 due to ITP. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.
Diagnosis and treatment of idiopathic thrombocytopenic purpura: The diagnosis of ITP is a diagnosis of exclusion. Abstract Idiopathic thrombocytopenic purpura ITP is an immune-mediated thrombocytopenia.
Not to be confused with autoimmune thrombotic thrombocytopenic purpura.
A report of 66 cases. Helicobacter pylori and autoimmune neutropenia.
The mechanism of action of anti-D is not fully understood. Spontaneous remissions are unusual in adults. Patient was admitted in Hematology Ward, Government General Hospital, Chennai on and treatment was started as described below: Helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpura. Chemistry of Plants That Changed the World.